Correction: A whole genome association study of mother-to-child transmission of HIV in Malawi

  • Bonnie R Joubert1Email author,

    Affiliated with

    • Ethan M Lange2, 3, 4,

      Affiliated with

      • Nora Franceschini1,

        Affiliated with

        • Victor Mwapasa5,

          Affiliated with

          • Kari E North1, 4,

            Affiliated with

            • Steven R Meshnick1 and

              Affiliated with

              • The NIAID Center for HIV/AIDS Vaccine Immunology

                Affiliated with

                Genome Medicine20102:76

                DOI: 10.1186/gm197

                Received: 1 October 2010

                Accepted: 11 October 2010

                Published: 11 October 2010

                Abstract

                A correction to: Bonnie R Joubert, Ethan M Lange, Nora Franceschini, Victor Mwapasa, Kari E North, Steven R Meshnick andthe NIAID Center for HIV/AIDS Vaccine Immunology. A whole genome association study of mother-to-child transmission of HIV in Malawi. Genome Medicine 2010, 2 :17.

                We wish to report some corrections to our study [1], none of which alters the interpretation of the data or the conclusions drawn. After publication of this work we noted that the sample size required further clarification.

                Results

                A total of 246 infants (114 cases, 132 controls; 116 males, 121 females, 9 with imputed gender) passed laboratory quality control. Statistical quality control removed 15 individuals for low genotyping, resulting in a total of 231 individuals (103 cases, 128 controls; 114 males, 117 females). Of the 655,352 SNPs tested, 68,297 failed statistical quality control due to HWE P < 0.001 in the controls (N = 431), low genotyping rate (N = 21,589), or for MAF < 0.01 (N = 53,477), where some overlap of SNPs across exclusion criteria existed. Results were presented for 587,055 SNPs.

                Additional data files

                Additional data files 1 and 2 containing the corrected data are available online with this article.

                Declarations

                Authors’ Affiliations

                (1)
                Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina
                (2)
                Department of Genetics, School of Medicine, University of North Carolina
                (3)
                Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina
                (4)
                Carolina Center for Genome Sciences, University of North Carolina
                (5)
                College of Medicine, University of Malawi

                References

                1. Joubert Bonnie R, Lange Ethan M, Franceschini Nora, Mwapasa Victor, North Kari E, Meshnick Steven R, the NIAID Center for HIV/AIDS Vaccine Immunology: A whole genome association study of mother-to-child transmission of HIV in Malawi. Genome Medicine 2010, 2: 17.PubMed

                Copyright

                © Joubert et al. 2010

                This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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