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Table 1 Baseline characteristics among women included in hormone-therapy proteomics project (n = 50 for E+P and for E-alone trials)

From: Postmenopausal estrogen and progestin effects on the serum proteome

  E+P E-alone  
  Number % Number % Pvaluea
Age group at screening, years      0.20
   50-59 17 34.0 25 50.0  
   60-69 21 42.0 13 26.0  
   70-79 12 24.0 12 24.0  
Minority race/ethnicity 3 6.0 8 16.0 0.20
Postmenopausal hormone therapy use      0.69
   Never used 31 62.0 26 52.0  
   Past user 15 30.0 19 38.0  
   Current user (3-month 'wash out' before enrollment) 4 8.0 5 10.0  
Smoking      0.50
   Never 34 69.4 29 58.0  
   Past 14 28.6 19 38.0  
   Current 1 2.0 2 4.0  
Parity      0.74
   Never pregnant/no term pregnancy 6 12.0 4 8.0  
   ≥ 1term pregnancy 44 88.0 46 92.0  
Age at first birth, years      0.38
   <20 8 21.1 15 34.1  
   20-29 29 76.3 27 61.4  
   30+ 1 2.6 2 4.5  
Treated diabetes 2 4.0 7 14.0 0.16
Treated for hypertension or BP ≥ 140/90 15 31.9 17 37.0 0.67
History of high cholesterol requiring pills 2 4.3 2 4.5 >0.99
Statin use at baseline 0 0.0 2 4.0 0.49
Aspirin (≥ 80 mg) use at baseline 8 16.0 8 16.0 >0.99
History of MI 1 2.0 0 0.0 >0.99
History of angina 1 2.0 3 6.0 0.62
History of CABG/PTCA 1 2.0 0 0.0 >0.99
History of DVT or PE 1 2.0 0 0.0 >0.99
Family history of breast cancer (female) 6 13.0 7 14.6 >0.99
History of fracture on or after age 55 3 8.3 1 3.1 0.62
Gail Model Five Year Risk of Breast Cancer      0.26
   <1 7 14.0 10 20.0  
   1 - <2 31 62.0 34 68.0  
   2 - <5 12 24.0 6 12.0  
Number of falls in last 12 months      0.97
   None 31 66.0 30 69.8  
   1 time 9 19.1 7 16.3  
   2 times 6 12.8 6 14.0  
   3 or more times 1 2.1 0 0.0  
  Mean SD Mean SD P value b
Age at screening, years 63.2 7.2 61.4 7.9 0.24
Body-mass index (BMI), kg/m2 28.8 6.0 31.1 6.1 0.05
  1. aP value based on Fisher's Exact test of association. bP value based on two-sample t test.
  2. MI = myocardial infarction; CABG/PCTA = coronary artery bypass graft/percutaneous transluminal angiography; DVT = deep vein thrombosis; PE = pulmonary embolus.