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Tumor immune microenvironment and immunotherapy

Look out for our special issue content being published over the next several months.

Evolving neoantigen profiles

Alberto Bardelli and colleagues report their results on longitudinal monitoring of the neoantigen landscape in colorectal cancers.

Rapid detection of drug resistance

Taane Clark and colleagues present their new software for detection of drug-resistant Mycobacterium tuberculosis.

Radiation therapy and anti-tumor immunity

Sandra Demaria and colleagues share their opinion on radiation therapy and exposing immunogenic mutations to the immune system.

A Decade of Genome Medicine

2019 is the 10th anniversary of Genome Medicine! This collection revisits some of our favorite articles. 

Reviews, Research Highlights and Commentaries

Read authoritative Reviews, Opinions and other content commissioned by the Genome Medicine Editors from leading researchers:

Reviews

Research Highlights

Commentaries (including Editorials, Comments, Opinions, Q&As and Meeting reports)

Articles

  1. Content type: Research

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    Authors: Giuseppe Rospo, Annalisa Lorenzato, Nabil Amirouchene-Angelozzi, Alessandro Magrì, Carlotta Cancelliere, Giorgio Corti, Carola Negrino, Vito Amodio, Monica Montone, Alice Bartolini, Ludovic Barault, Luca Novara, Claudio Isella, Enzo Medico, Andrea Bertotti, Livio Trusolino…

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Focus: Immunology in Health and Disease

Read the latest papers on immunology across BMC flagship journals.

A step beyond the hygiene hypothesis—immune-mediated classes determined in a population-based study
Vladeta Ajdacic-Gross, Margot Mutsch, Stephanie Rodgers, Anja Tesic, Mario Müller, Erich Seifritz, En-Young N. Wagner, Roland von Känel, Markus A. Landolt, Nina Steinemann, Viktor von Wyl, Enrique Castelao, Marie-Pierre F. Strippoli, Jennifer Glaus, Caroline Vandeleur, Pedro M. Marques-Vidal, Peter Vollenweider and Martin Preisig
Published in BMC Medicine on: 9 April 2019

Time-resolved transcriptome and proteome landscape of human regulatory T cell (Treg) differentiation reveals novel regulators of FOXP3
Angelika Schmidt, Francesco Marabita, Narsis A. Kiani, Catharina C. Gross, Henrik J. Johansson, Szabolcs Éliás, Sini Rautio, Matilda Eriksson, Sunjay Jude Fernandes, Gilad Silberberg, Ubaid Ullah, Urvashi Bhatia, Harri Lähdesmäki, Janne Lehtiö, David Gomez-Cabrero, Heinz Wiendl, Riitta Lahesmaa and Jesper Tegnér
Published in BMC Biology on: 7 May 2018

Single-cell transcriptomics reveal that PD-1 mediates immune tolerance by regulating proliferation of regulatory T cells
Cherry S. Leung, Kevin Y. Yang, Xisheng Li, Vicken W. Chan, Manching Ku, Herman Waldmann, Shohei Hori, Jason C. H. Tsang, Yuk Ming Dennis Lo and Kathy O. Lui
Published in Genome Medicine on: 20 September 2018

Exploring the genetic basis of human population differences in DNA methylation and their causal impact on immune gene regulation
Lucas T. Husquin, Maxime Rotival, Maud Fagny, Hélène Quach, Nora Zidane, Lisa M. McEwen, Julia L. MacIsaac, Michael S. Kobor, Hugues Aschard, Etienne Patin and Lluis Quintana-Murci
Published in Genome Biology on: 18 December 2018

Aims and scope

Genome Medicine publishes research and reviews that describe important advances in the application of genetics, genomics and multi-omics to understand, diagnose and treat disease. Areas covered include, but are not limited to: precision medicine, novel methods and software, cancer genomics, disease genomics and epigenomics, immunogenomics, infectious disease, microbiome and systems medicine.

Article collections

Special issue
Tumor immune microenvironment and immunotherapy
Guest editors: Zlatko Trajanoski and Noel de Miranda

Special issue
From genome integrity to cancer
Guest editor: Serena Nik-Zainal

Special issue
Genomics of infection and immunity
Guest editors: Bali Pulendran and Mark Davis

Special issue
Disease Neurogenomics
Guest editors: Joseph Buxbaum and Catalina Betancur

See all article collections

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