Genome Medicine

Special Issue: Genomics of Infection and Immunity

Read the latest articles in our new special issue, guest-edited by Bali Pulendran and Mark Davis

Call for Papers - Genome Integrity to Cancer: Mechanisms and Translational Opportunities

The Call for Papers is now open for our Fall 2018 special issue, guest-edited by Serena Nik-Zainal

Lineage diversity in glioma

Newly resolved heterogeneity of glioma and microenvironmental cells with single-cell RNA-seq

Addressing "druggability" in precision oncology

A multi-omic approach to characterize potentially druggable alterations across 22 cancer types

Understanding variation in healthy immune response

New analysis of factors contributing to the humoral immune response to 15 common pathogens and vaccines, in a large cohort of healthy individuals

Video abstract: A new blood test uses DNA methylation to detect and predict the spread of breast cancer

A study by Widschwendter and colleagues suggests that serum DNAme markers can diagnose fatal breast cancers up to one year in advance of current diagnosis and enable individualized treatment which may even commence before obtaining radiological evidence – see the video abstract for a graphic summary of the paper.

Recent
Most accessed

Content type: Research
| 23 August 2018

Genomic exploration of sequential clinical isolates reveals a distinctive molecular signature of persistent Staphylococcus aureus bacteraemia

Authors: Stefano G. Giulieri, Sarah L. Baines, Romain Guerillot, Torsten Seemann, Anders Gonçalves da Silva, Mark Schultz, Ruth C. Massey, Natasha E. Holmes, Timothy P. Stinear and Benjamin P. Howden
Content type: Research
| 7 August 2018

A genome-wide siRNA screen identifies a druggable host pathway essential for the Ebola virus life cycle

Authors: Scott Martin, Abhilash I. Chiramel, Marie Luisa Schmidt, Yu-Chi Chen, Nadia Whitt, Ari Watt, Eric C. Dunham, Kyle Shifflett, Shelby Traeger, Anne Leske, Eugen Buehler, Cynthia Martellaro, Janine Brandt, Lisa Wendt, Andreas Müller, Stephanie Peitsch…
Content type: Software
| 3 August 2018

Exploring the OncoGenomic Landscape of cancer

Authors: Lidia Mateo, Oriol Guitart-Pla, Miquel Duran-Frigola and Patrick Aloy
Content type: Comment
| 1 August 2018

Causality in dietary interventions—building a case for gut microbiota

Authors: Yan Y. Lam, Chenhong Zhang and Liping Zhao
Content type: Research
| 27 July 2018

Integrative omics analyses broaden treatment targets in human cancer

Authors: Sohini Sengupta, Sam Q. Sun, Kuan-lin Huang, Clara Oh, Matthew H. Bailey, Rajees Varghese, Matthew A. Wyczalkowski, Jie Ning, Piyush Tripathi, Joshua F. McMichael, Kimberly J. Johnson, Cyriac Kandoth, John Welch, Cynthia Ma, Michael C. Wendl, Samuel H. Payne…

Most recent articles RSS

View all articles

Content type: Comment
| 1 April 2016

The virome: a missing component of biological interaction networks in health and disease

Authors: Scott A. Handley
Content type: Research
| 10 May 2016

Alterations in fecal microbiota composition by probiotic supplementation in healthy adults: a systematic review of randomized controlled trials

Authors: Nadja B. Kristensen, Thomas Bryrup, Kristine H. Allin, Trine Nielsen, Tue H. Hansen and Oluf Pedersen
Content type: Research
| 19 April 2017

Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden

Authors: Zachary R. Chalmers, Caitlin F. Connelly, David Fabrizio, Laurie Gay, Siraj M. Ali, Riley Ennis, Alexa Schrock, Brittany Campbell, Adam Shlien, Juliann Chmielecki, Franklin Huang, Yuting He, James Sun, Uri Tabori, Mark Kennedy, Daniel S. Lieber…
Content type: Open debate
| 31 January 2013

Constructing narratives of heroism and villainy: case study of Myriad's BRACAnalysis^® compared to Genentech's Herceptin^®

Authors: A Lane Baldwin and Robert Cook-Deegan
Content type: Research
| 27 August 2015

Pharmacological inhibition of DNA-PK stimulates Cas9-mediated genome editing

Authors: Francis Robert, Mathilde Barbeau, Sylvain Éthier, Josée Dostie and Jerry Pelletier

Most accessed articles RSS

View all articles

Aims and scope

Genome Medicine publishes research and reviews that describe important advances in the application of genetics, genomics and multi-omics to understand, diagnose and treat disease. Areas covered include, but are not limited to: precision medicine, novel methods and software, cancer genomics, disease genomics and epigenomics, immunogenomics, infectious disease, microbiome and systems medicine.

Article collections

Special issue
Genomics of infection and immunity
Guest editors: Bali Pulendran and Mark Davis

Special issue
Disease Neurogenomics
Guest editors: Joseph Buxbaum and Catalina Betancur

Collection
Highlights from infectious disease genomics

Special issue
Genomic technologies: development and clinical application
Guest editor: Stephen Kingsmore

See all article collections

Latest Tweets

From the blog

CONSORT-SPI 2018: announcing an extension for randomized controlled trials of social and psychological interventions

31 July 2018
On consciousness and the unconscious

27 July 2018
Which medications prevent emergency hospital admissions?

26 July 2018

Genome Medicine

Special Issue: Genomics of Infection and Immunity

Call for Papers - Genome Integrity to Cancer: Mechanisms and Translational Opportunities

Lineage diversity in glioma

Addressing "druggability" in precision oncology

Understanding variation in healthy immune response

Video abstract: A new blood test uses DNA methylation to detect and predict the spread of breast cancer

Articles

Genomic exploration of sequential clinical isolates reveals a distinctive molecular signature of persistent Staphylococcus aureus bacteraemia

A genome-wide siRNA screen identifies a druggable host pathway essential for the Ebola virus life cycle

Exploring the OncoGenomic Landscape of cancer

Causality in dietary interventions—building a case for gut microbiota

Integrative omics analyses broaden treatment targets in human cancer

The virome: a missing component of biological interaction networks in health and disease

Alterations in fecal microbiota composition by probiotic supplementation in healthy adults: a systematic review of randomized controlled trials

Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden

Constructing narratives of heroism and villainy: case study of Myriad's BRACAnalysis^® compared to Genentech's Herceptin^®

Pharmacological inhibition of DNA-PK stimulates Cas9-mediated genome editing

Aims and scope

Article collections

Latest Tweets

From the blog

CONSORT-SPI 2018: announcing an extension for randomized controlled trials of social and psychological interventions

On consciousness and the unconscious

Which medications prevent emergency hospital admissions?

Follow

2017 Journal Metrics

Genome Medicine

Contact us