Genome Medicine

Genomic Technologies: New special issue

Ahronian and Corcoran review recent advances in understanding tumor heterogeneity and resistance to targeted therapies, focusing on combination kinase inhibitors, and discuss approaches to address these issues in the clinic.

Featured Video: Genomic analyses provide insights into the microbiome of patients with early Parkinson's disease

A study by Bedarf, Hildebrand and colleagues reveals marked differences in the microbial composition and viral abundances between early stage, L-DOPA-naïve Parkinson’s disease patients and healthy controls, and highlights functional differences in the microbial metabolism in Parkinson’s patients – see the video abstract for a graphic summary of the paper.

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Genome Medicine publishes research and reviews that describe important advances in the application of genetics, genomics and multi-omics to understand, diagnose and treat disease. Areas covered include, but are not limited to: precision medicine, novel methods and software, cancer genomics, disease genomics and epigenomics, immunogenomics, infectious disease, microbiome and systems medicine.

Article collections

Special issue
Genomic technologies: development and clinical application
Guest editor: Stephen Kingsmore

Special issue
Precision cancer medicine
Guest editors: Michael Berger and Eliezer Van Allen

Special issue
Translating the microbiome: health and disease
Guest editor: Curtis Huttenhower

Special issue
Immunogenomics in health and disease
Guest editor: Robert Holt

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The gut microbiota and Parkinson’s disease – what we know so far

Published on: 16 August 2017
Critical Care celebrates 20 years

Published on: 13 August 2017
The Renin-Angiotensin System: a fresh new direction in the treatment of depression

Published on: 09 August 2017

Genome Medicine

Genomic Technologies: New special issue

Disease Neurogenomics: Call for papers

Featured Review: Strategies for monitoring and combating resistance to combination kinase inhibitors for cancer therapy

Featured Video: Genomic analyses provide insights into the microbiome of patients with early Parkinson's disease

Articles

Phenotypic and molecular characterisation of CDK13-related congenital heart defects, dysmorphic facial features and intellectual developmental disorders

Genomic technologies—from tools to therapies

Post-mortem molecular profiling of three psychiatric disorders

Longitudinal genomic surveillance of multidrug-resistant Escherichia coli carriage in a long-term care facility in the United Kingdom

Next-generation sequencing to monitor the spread of antimicrobial resistance

The virome: a missing component of biological interaction networks in health and disease

Alterations in fecal microbiota composition by probiotic supplementation in healthy adults: a systematic review of randomized controlled trials

Constructing narratives of heroism and villainy: case study of Myriad's BRACAnalysis^® compared to Genentech's Herceptin^®

Pharmacological inhibition of DNA-PK stimulates Cas9-mediated genome editing

Genomic analysis of 63,220 tumors reveals insights into tumor uniqueness and targeted cancer immunotherapy strategies

Aims and scope

Article collections

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From the blog

The gut microbiota and Parkinson’s disease – what we know so far

Critical Care celebrates 20 years

The Renin-Angiotensin System: a fresh new direction in the treatment of depression

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