Table 2 Relationship between clinical and biochemical characteristics and histological groups in infants with biliary atresia
From: Staging of biliary atresia at diagnosis by molecular profiling of the liver
Patient characteristic | Inflammatory subtype, N = 14 | Fibrosing subtype, N = 17 | Total, N = 31a | P-valueb |
|---|---|---|---|---|
Sex, N (%) | Â | Â | Â | Â |
   Female | 5 (36) | 6 (35) | 11 (35) | 1.0 |
   Male | 9 (64) | 11 (65) | 20 (65) |  |
Race, N (%) | Â | Â | Â | Â |
   White | 11 (79) | 16 (94) | 27 (87) | 1.0 |
   Black | 0 (0) | 0 (0) | 0 (0) | 1.0 |
   Asian | 2 (14) | 1 (6) | 3 (10) | 1.0 |
   Other | 1 (7) | 0 (0) | 1 (3) | 1.0 |
Ethnicity, N (%) | Â | Â | Â | Â |
   Hispanic | 1 (7) | 2 (12) | 3 (10) | 1.0 |
   Nonhispanic | 13 (93) | 15 (88) | 28 (90) |  |
Age in days, median (25-75%) | 63 (55-65) | 66 (51-77) | 63 (51-73) | 0.3 |
Clinical type | Â | Â | Â | Â |
   BASM N (%) | 1 (7) | 1 (6) | 2 (7) | 1.0 |
   Perinatal N (%) | 13 (93) | 16 (94) | 29 (93) |  |
Mean CB at diagnosisc | 5.1 ± 1.6 | 5.8 ± 2.5 | 5.6 ± 2.2 | 0.5 |
Mean ALT at diagnosisc | 196 ± 150 | 192 ± 120 | 194 ± 136 | 1.0 |
Mean CB at 3 months after HPEc | 2.3 ± 3.7 | 3.0 ± 3.5 | 2.6 ± 3.6 | 0.7 |
Weight Z-score at 6 months after HPEc | -1.1 ± 0.9 | -1.8 ± 1.9 | -1.4 ± 1.4 | 0.3 |
Presence of cholangitis, N (%) | 5 (56) | 10 (59) | 15 (58) | 1.0 |
Presence of ascites, N (%) | 4 (36) | 9 (53) | 13 (47) | 0.7 |