|
System
|
Gene
|
Polymorphism
|
References
|
|---|
|
Hemostasis
|
Factor II (prothrombin) (+176930)
|
c.20210G > A
|
[39, 41–43]
|
| |
Factor V (Leiden) (*612309)
|
p.Arg506Gln
|
[33–40]
|
| |
Factor XIII (+134570)
|
p.Val34Leu
|
[39, 44, 45]
|
|
Renin-angiotensin system
|
ACE (+106180)
|
Insertion/deletion
|
[40, 48–51]
|
| |
AT1R (*106165)
|
c.1166A > C
|
[52–55]
|
|
Nitric-oxide-synthase system
|
eNOS (+163729)
|
p.Glu298Asp
|
[56–58]
|
|
Homocysteine metabolism
|
MTHFR (*607093)
|
c.677C > T and c.1298A > C
|
[43, 59–61]
|
|
Lipid metabolism
|
APOE (+107741)
|
ε4, ε3, ε2
|
[40, 46, 62–66]
|
- ACE, angiotensin converting enzyme; APOE, apolipoprotein E; AT1R, angiotensin-receptor; eNOS, endothelial nitric oxide synthase; MTHFR, 5,10-methylenetetrahydrofolate reductase.
