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Table 3 Functional SNPs associated with ischemic stroke

From: Three periods of one and a half decade of ischemic stroke susceptibility gene research: lessons we have learned

System Gene Polymorphism References
Lipid metabolism APOA5 (*606368) g.-1131T > C, c.1259T > C, c.56C > G, c.IVS3+476G > A [8288]
  APOCIII (*107720) g.-2854T > G, g.-455C > T, g.-482C > T, c.3238C > G [7376]
  LPL (*609708) p.Asn291Ser [9295]
  GCKR (*600842) c.1337C > T [104]
  MLXIPL (*605678) rs17145738, rs3812316 [105]
  GALNT (*602274) rs4846914 [104]
Signal transduction PDE4D (*600129) Six SNPs, haplotypes [96100]
Inflammation ALOX5AP (*603700) Seven SNPs, haplotypes [97, 100103]
  1. ALOX5AP, arachidonate 5-lipoxygenase-activating protein; APOA5, apolipoprotein A5; APOCIII, apolipoprotein CIII; LPL, lipoprotein lipase; PDE4D, phosphodiesterase 4D.