From: Genome-based prediction of common diseases: methodological considerations for future research
Disease | Coronary heart disease | Systemic lupus erythematosus | Hypertriglyceridemia | |||
---|---|---|---|---|---|---|
AUC* | 0.55 | 0.67 | 0.80 | |||
Reference | [35] | [28] | [12] | |||
Genes and effect estimates | Â | Â | Â | Â | Â | Â |
 | AGT | 1.28 (1.02, 1.61) | HLA | 2.36 (2.11, 2.64)‡ | APOA5 | 7.36 (3.98, 13.6) |
 | ACE | 1.18 (0.97, 1.44) | ITGAM | 1.62 (1.47,1.78)‡ | APOA5 | 5.57 (3.13, 9.90) |
 | AGTR1 | 1.21 (1.00, 1.45) | IRF5/TNPO3 | 1.54 (1.40, 1.70)‡ | TBL2 | 2.81 (1.46, 5.24) |
 | CYP11B2 | 1.22 (1.01, 1.48) | KIAA1542 | 0.78 (0.73, 0.85) | APOE | 2.14 (1.31, 3.49) |
 | ADD1 | 1.22 (1.01, 1.47) | PXK | 1.25 (1.16, 1.35) | GCKR | 2.11 (1.21, 3.67) |
 | GNB3 | 0.72 (0.52, 1.01) | rs10798269 | 0.82 (0.76, 0.88) | GALNT2 | 2.10 (1.15, 3.81) |
 |  |  |  |  | TRIB1 | 2.02 (1.24, 3.30) |