From: Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data
 | Discovery dataset (N = 8,844) | Validation datasetb (N = 3,606) | ||
---|---|---|---|---|
 | Case | Control | Case | Control |
Stratuma | (N = 2,124) | (N = 6,720) | (N = 1,618) | (N = 1,988) |
IMSGC UK, Affy 500K | 17.5% | 40.9% | - | - |
IMSGC US, Affy 500K | 13.2% | 23.3% | - | - |
BWH, Affy 6.0 | 32.2% | 23.9% | - | - |
Gene MSA CH, Illumina 550K | 9.6% | 2.9% | - | - |
Gene MSA NL, Illumina 550K | 8.9% | 3.1% | - | - |
Gene MSA US, Illumina 550K | 18.6% | 5.9% | - | - |
Male | 27.9% | 50.3% | 27.5% | 38.1% |
Female | 72.1% | 49.7% | 72.5% | 61.9% |
DRB1*15:01 + | 52.7% | 25.1% | 56.9% | 29.8% |
DRB1*15:01 - | 47.3% | 74.9% | 43.1% | 70.2% |