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Table 1 Demographic statistics of study participants

From: Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data

 

Discovery dataset (N = 8,844)

Validation datasetb (N = 3,606)

 

Case

Control

Case

Control

Stratuma

(N = 2,124)

(N = 6,720)

(N = 1,618)

(N = 1,988)

IMSGC UK, Affy 500K

17.5%

40.9%

-

-

IMSGC US, Affy 500K

13.2%

23.3%

-

-

BWH, Affy 6.0

32.2%

23.9%

-

-

Gene MSA CH, Illumina 550K

9.6%

2.9%

-

-

Gene MSA NL, Illumina 550K

8.9%

3.1%

-

-

Gene MSA US, Illumina 550K

18.6%

5.9%

-

-

Male

27.9%

50.3%

27.5%

38.1%

Female

72.1%

49.7%

72.5%

61.9%

DRB1*15:01 +

52.7%

25.1%

56.9%

29.8%

DRB1*15:01 -

47.3%

74.9%

43.1%

70.2%

  1. aDatasets described in [24]. In each pair of matched cases and controls, all subjects are genotyped using the same genome-wide platform. bDatasets described in [12], with 1,618 Australian and New Zealand cases (Illumina Hap370CNV) matched with 1,988 US controls (Illumina Infinium).