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Figure 2 | Genome Medicine

Figure 2

From: Predictive genetic testing for the identification of high-risk groups: a simulation study on the impact of predictive ability

Figure 2

Sensitivity and positive predictive value (PPV) for different thresholds. High-risk group is defined as all individuals with a genetic risk score equal to or higher than the chosen threshold. Genetic risk scores are based on 50 genetic risk variants. (a-c) The OR indicates the value of the odds ratio for each risk variant: 1.1 (a), 1.5 (b) and 2 (c). Disease risk is 30%.

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Genome Medicine

ISSN: 1756-994X

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