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Table 1 Copy number variation profile of the p38 pathway

From: Gene expression and network-based analysis reveals a novel role for hsa-miR-9 and drug control over the p38 network in glioblastoma multiforme progression

Gene symbol

Tumor

Normal

Amplified genes

  

   HSP27

21%

2%

   CREB1

27%

16%

   TCF3

14%

2%

   ER81

45%

6%

   CDC25B

36%

20%

Deleted genes

  

   MAPKAPK3

20%

11%

   LSP1

31%

25%

   TH

37%

14%

   YWHAZ

63%

27%

   ALOX5

68%

7%

   RAF1

13%

9%

  1. Of the 13 genes in the p38 pathway, 11 show significant change (according to Mann-Whitney U test) in copy number, amplification or deletion, between the tumor and its matched normal sample across all patients.