Gene symbol
|
Tumor
|
Normal
|
---|
Amplified genes
| | |
HSP27
|
21%
|
2%
|
CREB1
|
27%
|
16%
|
TCF3
|
14%
|
2%
|
ER81
|
45%
|
6%
|
CDC25B
|
36%
|
20%
|
Deleted genes
| | |
MAPKAPK3
|
20%
|
11%
|
LSP1
|
31%
|
25%
|
TH
|
37%
|
14%
|
YWHAZ
|
63%
|
27%
|
ALOX5
|
68%
|
7%
|
RAF1
|
13%
|
9%
|
- Of the 13 genes in the p38 pathway, 11 show significant change (according to Mann-Whitney U test) in copy number, amplification or deletion, between the tumor and its matched normal sample across all patients.