Skip to main content

Table 2 Glioblastoma drug targets

From: Gene expression and network-based analysis reveals a novel role for hsa-miR-9 and drug control over the p38 network in glioblastoma multiforme progression

Drug name Target Pathway
Accutane RARA MAPK inactivation of SMRT co-repressor
CCNU STMN4 Signaling mediated by p38-gamma and p38-delta pathway
Celebrex COX2 Signaling mediated by p38-alpha and p38-beta pathway
Cis-retinoic acid RARA MAPK inactivation of SMRT co-repressor
Sorafenib RAF1 p38 signaling mediated by MAPKAP kinases
Tamoxifen ESR1 Signaling mediated by p38-alpha and p38-beta pathway
  1. The table lists 6 of the 69 drugs in TCGA clinical dataset that target genes in the p38/MAPKAP pathway. MAPK, mitogen-activated protein kinase.