From: Inferring novel gene-disease associations using Medical Subject Heading Over-representation Profiles
Gene | Entrez gene | Predicted similarity | Rank | Percentile | Mutations | Deletions | Passenger probability: low rates | Passenger probability: mid rates | Passenger probability: high rates |
---|---|---|---|---|---|---|---|---|---|
TP53 | 7157 | 1.24E+08 | 11 | 100 | 18 | 2 | < 0.001 | < 0.001 | < 0.001 |
CDKN2A | 1029 | 8.29E+07 | 135 | 99 | 2 | 16 | < 0.001 | < 0.001 | < 0.001 |
KRAS | 3845 | 6.95E+07 | 266 | 99 | 24 | 0 | < 0.001 | < 0.001 | < 0.001 |
TGFBR2 | 7048 | 6.76E+07 | 288 | 99 | 3 | 1 | < 0.001 | 0.001 | 0.003 |
EP300 | 2033 | 6.37E+07 | 351 | 99 | 2 | 0 | 0.176 | 0.482 | 0.984 |
SMAD4 | 4089 | 6.14E+07 | 386 | 98 | 8 | 6 | < 0.001 | < 0.001 | < 0.001 |
ELN | 2006 | 5.57E+07 | 509 | 98 | 2 | 0 | 0.115 | 0.372 | 0.413 |
F8 | 2157 | 5.51E+07 | 530 | 98 | 2 | 0 | 0.165 | 0.482 | 0.853 |
SCN5A | 6331 | 5.18E+07 | 629 | 98 | 2 | 0 | 0.176 | 0.482 | 1.000 |
PRKCG | 5582 | 4.77E+07 | 798 | 97 | 2 | 0 | 0.115 | 0.372 | 0.413 |
TPO | 7173 | 4.71E+07 | 831 | 97 | 2 | 0 | 0.115 | 0.375 | 0.694 |
PPP1R3A | 5506 | 4.50E+07 | 946 | 96 | 2 | 0 | 0.115 | 0.477 | 0.694 |
SMARCA4 | 6597 | 4.04E+07 | 1243 | 95 | 2 | 0 | 0.062 | 0.183 | 0.413 |
COL5A1 | 1289 | 3.72E+07 | 1518 | 94 | 2 | 0 | 0.176 | 0.482 | 0.984 |
MEP1A | 4224 | 3.38E+07 | 1895 | 92 | 2 | 0 | 0.062 | 0.183 | 0.413 |
IL2RG | 3561 | 2.95E+07 | 2652 | 89 | 1 | 0 | 0.004 | 0.016 | 0.997 |
ATP10A | 57194 | 2.77E+07 | 2974 | 88 | 2 | 0 | 0.176 | 0.482 | 1.000 |
MYH2 | 4620 | 2.71E+07 | 3063 | 88 | 2 | 0 | 0.165 | 0.477 | 0.853 |
GRIA3 | 2892 | 2.62E+07 | 3281 | 87 | 1 | 1 | 0.017 | 0.069 | 0.999 |
ABCA7 | 10347 | 2.56E+07 | 3426 | 86 | 2 | 0 | 0.033 | 0.139 | 0.201 |
DLG3 | 1741 | 2.51E+07 | 3540 | 86 | 1 | 0 | 0.003 | 0.015 | 0.997 |
DLC1 | 10395 | 2.47E+07 | 3645 | 86 | 2 | 0 | 0.176 | 0.482 | 1.000 |
GLTSCR1 | 29998 | 2.06E+07 | 5082 | 80 | 2 | 0 | 0.062 | 0.183 | 0.405 |
PCSK6 | 5046 | 2.02E+07 | 5240 | 79 | 2 | 0 | 0.176 | 0.482 | 0.911 |
EVPL | 2125 | 2.00E+07 | 5329 | 79 | 2 | 0 | 0.176 | 0.482 | 0.942 |
NRG2 | 9542 | 1.95E+07 | 5537 | 78 | 2 | 0 | 0.165 | 0.477 | 0.853 |
SLITRK5 | 26050 | 1.93E+07 | 5655 | 78 | 2 | 0 | 0.165 | 0.477 | 0.853 |
SEMA5B | 54437 | 1.92E+07 | 5713 | 77 | 2 | 0 | 0.062 | 0.183 | 0.413 |
DPP6 | 1804 | 1.86E+07 | 6025 | 76 | 3 | 0 | 0.009 | 0.079 | 0.201 |
PCDH15 | 65217 | 1.84E+07 | 6162 | 76 | 4 | 0 | < 0.001 | 0.017 | 0.048 |
FMN2 | 56776 | 1.82E+07 | 6266 | 75 | 2 | 0 | 0.176 | 0.482 | 0.911 |
CACNA2D1 | 781 | 1.77E+07 | 6597 | 74 | 1 | 0 | 0.001 | 0.004 | 0.989 |
DLEC1 | 9940 | 1.70E+07 | 7039 | 72 | 2 | 0 | 0.176 | 0.482 | 0.911 |
MLL3 | 58508 | 1.69E+07 | 7090 | 72 | 6 | 0 | < 0.001 | < 0.001 | < 0.001 |
PB1 | 55193 | 1.63E+07 | 7597 | 70 | 2 | 0 | 0.165 | 0.477 | 0.853 |
LRRN3 | 54674 | 1.60E+07 | 7856 | 69 | 2 | 0 | 0.062 | 0.183 | 0.405 |
CYFIP1 | 23191 | 1.56E+07 | 8225 | 67 | 3 | 0 | 0.009 | 0.079 | 0.201 |
SF3B1 | 23451 | 1.55E+07 | 8290 | 67 | 3 | 0 | 0.009 | 0.079 | 0.201 |
PXDN | 7837 | 1.55E+07 | 8302 | 67 | 2 | 0 | 0.176 | 0.482 | 1.000 |
TNR | 7143 | 1.54E+07 | 8453 | 66 | 2 | 0 | 0.176 | 0.482 | 0.911 |
SN | 6614 | 1.53E+07 | 8484 | 66 | 2 | 0 | 0.176 | 0.482 | 1.000 |
SLC6A15 | 55117 | 1.53E+07 | 8488 | 66 | 2 | 0 | 0.062 | 0.183 | 0.405 |
ARID1A | 8289 | 1.51E+07 | 8688 | 66 | 2 | 0 | 0.176 | 0.482 | 0.984 |
SLC1A6 | 6511 | 1.48E+07 | 8908 | 65 | 2 | 0 | 0.115 | 0.477 | 0.694 |
LRRTM4 | 80059 | 1.46E+07 | 9064 | 64 | 2 | 0 | 0.062 | 0.183 | 0.413 |
GALNT13 | 114805 | 1.42E+07 | 9651 | 62 | 2 | 0 | 0.062 | 0.183 | 0.405 |
GUCY1A2 | 2977 | 1.39E+07 | 9964 | 60 | 2 | 0 | 0.062 | 0.183 | 0.405 |
ZNF638 | 27332 | 1.37E+07 | 10174 | 60 | 2 | 0 | 0.115 | 0.375 | 0.694 |
PDZRN3 | 23024 | 1.33E+07 | 10522 | 58 | 2 | 0 | 0.033 | 0.082 | 0.201 |
DOCK2 | 1794 | 1.33E+07 | 10612 | 58 | 2 | 0 | 0.062 | 0.183 | 0.405 |
MIZF | 25988 | 1.32E+07 | 10714 | 58 | 2 | 0 | 0.062 | 0.183 | 0.405 |
DACH2 | 117154 | 1.30E+07 | 10883 | 57 | 1 | 1 | 0.022 | 0.088 | 1.000 |
ST6GAL2 | 84620 | 1.26E+07 | 11302 | 55 | 2 | 0 | 0.115 | 0.375 | 0.694 |
KBTBD11 | 9920 | 1.19E+07 | 12083 | 52 | 1 | 1 | 0.006 | 0.025 | 0.998 |
CNTN5 | 53942 | 1.18E+07 | 12231 | 51 | 2 | 0 | 0.115 | 0.375 | 0.694 |
ABLIM2 | 84448 | 1.17E+07 | 12471 | 51 | 2 | 0 | 0.062 | 0.183 | 0.405 |
PCDH18 | 54510 | 1.14E+07 | 12864 | 49 | 2 | 0 | 0.115 | 0.375 | 0.694 |
ADAMTS20 | 80070 | 1.09E+07 | 13668 | 46 | 2 | 0 | 0.176 | 0.482 | 0.911 |
CDH10 | 1008 | 1.09E+07 | 13703 | 46 | 3 | 0 | < 0.001 | 0.017 | 0.048 |
KIAA1024 | 23251 | 1.09E+07 | 13715 | 46 | 2 | 0 | 0.115 | 0.375 | 0.694 |
TBX18 | 9096 | 1.08E+07 | 13821 | 45 | 2 | 0 | 0.062 | 0.183 | 0.413 |
LRFN5 | 145581 | 1.07E+07 | 13894 | 45 | 2 | 0 | 0.062 | 0.183 | 0.405 |
DEPDC2 | 80243 | 1.07E+07 | 13953 | 45 | 3 | 0 | 0.055 | 0.183 | 0.405 |
FMNL3 | 91010 | 1.05E+07 | 14376 | 43 | 2 | 0 | 0.055 | 0.179 | 0.405 |
TM7SF4 | 81501 | 1.03E+07 | 14681 | 42 | 2 | 0 | 0.055 | 0.179 | 0.405 |
OR10R2 | 343406 | 1.02E+07 | 15126 | 40 | 2 | 0 | 0.033 | 0.139 | 0.317 |
GPR133 | 283383 | 1.02E+07 | 15188 | 40 | 2 | 0 | 0.062 | 0.183 | 0.405 |
PCDH17 | 27253 | 1.01E+07 | 15355 | 39 | 2 | 0 | 0.062 | 0.183 | 0.405 |
BAI3 | 577 | 9.58E+06 | 16457 | 35 | 3 | 0 | 0.033 | 0.082 | 0.201 |
KIAA0774 | 23281 | 9.49E+06 | 16660 | 34 | 2 | 0 | 0.176 | 0.482 | 0.984 |
CTNNA2 | 1496 | 9.42E+06 | 16781 | 33 | 3 | 0 | 0.033 | 0.179 | 0.405 |
KLHDC4 | 54758 | 8.66E+06 | 18571 | 26 | 2 | 0 | 0.033 | 0.082 | 0.201 |
ZAN | 7455 | 8.45E+06 | 19030 | 25 | 2 | 0 | 0.176 | 0.482 | 0.984 |
DKFZP586P0123 | 26005 | 7.38E+06 | 20579 | 18 | 2 | 0 | 0.165 | 0.477 | 0.853 |
UNC13C | 440279 | 7.38E+06 | 20835 | 17 | 2 | 0 | 0.115 | 0.372 | 0.694 |
FLJ39155 | 133584 | 7.38E+06 | 21333 | 15 | 2 | 0 | 0.176 | 0.482 | 0.942 |
RASSF6 | 166824 | 7.38E+06 | 21543 | 15 | 2 | 0 | 0.062 | 0.183 | 0.405 |
OVCH1 | 341350 | 5.79E+06 | 24923 | 1 | 2 | 0 | 0.165 | 0.477 | 0.853 |
Q9H5F0_HUMAN | Â | NA | NA | NA | 3 | 0 | < 0.001 | 0.004 | 0.009 |
Q9H8A7_HUMAN | Â | NA | NA | NA | 2 | 0 | 0.165 | 0.477 | 0.853 |
FLJ46481 | 389197 | NA | NA | NA | 2 | 0 | 0.062 | 0.183 | 0.405 |
XR_017918.1 | Â | NA | NA | NA | 2 | 0 | 0.062 | 0.183 | 0.405 |
LOC441136 | 441136 | NA | NA | NA | 2 | 0 | 0.009 | 0.079 | 0.201 |