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Table 3 Combining HLA- C and IL28B genotypes to improve prediction

From: Pharmacogenomics of hepatitis C infections: personalizing therapy

Genotype

 

% of CHC

% of NSVR

% with NSVR

HLA-C

IL28B

   
 

rs8099917

   

Any

GG(1)

6

10

73

Any

G*

48

57

64

C2C2

Any

17

32

20

C2C2

G*(2)

8

12

80b

 

(1)+(2)

12

18a

77a

 

rs12979860

   

Any

TT(3)

15

19

68

Any

T*

68

79

63

C2C2

Any

17

21

64

C2C2

T*(4)

13

18

73

 

(3)+(4)

26

33

70

  1. CHC, chronic hepatitis C; NSVR, non-sustained viral response. aSlightly lower prediction percentage, but identifies a higher percentage of NSVR. bBest prediction. Data from Suppiah et al. [21].