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Table 3 Combining HLA- C and IL28B genotypes to improve prediction

From: Pharmacogenomics of hepatitis C infections: personalizing therapy

Genotype   % of CHC % of NSVR % with NSVR
HLA-C IL28B    
  rs8099917    
Any GG(1) 6 10 73
Any G* 48 57 64
C2C2 Any 17 32 20
C2C2 G*(2) 8 12 80b
  (1)+(2) 12 18a 77a
  rs12979860    
Any TT(3) 15 19 68
Any T* 68 79 63
C2C2 Any 17 21 64
C2C2 T*(4) 13 18 73
  (3)+(4) 26 33 70
  1. CHC, chronic hepatitis C; NSVR, non-sustained viral response. aSlightly lower prediction percentage, but identifies a higher percentage of NSVR. bBest prediction. Data from Suppiah et al. [21].