Figure 3

miRNAs are prognostic of recurrence and survival in an independent external dataset. Our prognostic miRNAs were used to generate models of OS in an independent external validation dataset. Of the 22 miRNA profile, 18 miRNAs could be mapped on the platform used in the external dataset. (A-C) These overlapping miRNAs (as well as smaller subsets of this profile) were used to generate survival risk prediction models. A consistent discriminatory trend was observed in the external dataset, despite a smaller sample size, fewer events and different array platform.