From: Chronic lymphocytic leukemia: molecular heterogeneity revealed by high-throughput genomics
Gene | Frequency (%) | Likely gene function |
---|---|---|
XPO1 | Nuclear export | |
CHD2 | Chromatin modification | |
POT1 | Telomere maintenance | |
HIST1H1E | 3 [75] | Histone protein |
NRAS | 3 [75] | Cell growth |
BCOR | 3 [75] | Apoptosis regulation |
ZMYM3 | Chromatin modification | |
RIPK1 | 3 [75] | Inflammatory pathway |
SAMHD1 | 3 [75] | Innate immune response |
KRAS | 2 [75] | Cell growth |
MED12 | 2 [75] | Gene transcription |
ITPKB | 2 [75] | B-cell signaling |
DDX3X | RNA helicase | |
EGR2 | 1 [75] | Transcription factor |
FBXW7 | Ubiquitination | |
KLHL6 | 2 [33] | B-cell receptor signaling |
MAPK1 | 3 [34] | MAP kinase |
LRP1B | 5 [40] | LDL receptor family |