Skip to main content

Table 6 Recommendations for applying consensus results to somatic mutation predictions

From: A simple consensus approach improves somatic mutation prediction accuracy

Prediction set Recommendations
Consensus Accurate, high-confidence predictions suitable for further analysis
Partial consensus Roughly equal numbers of genuine somatic mutations and false positives. Utility dependent on need to maximize sensitivity. Further filtering can be performed to improve confidence
No consensus Largely false positives; may be disregarded unless compelling biological interest exists. Explore using high-confidence list of variants from consensus