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Table 2 Number of validated true/false sSNVs detected using the five tools in a melanoma sample

From: Detecting somatic point mutations in cancer genome sequencing data: a comparison of mutation callers

Tool All sSNVs High confidence sSNVs
# TP # FP # TP # FP
JointSNVMix 119 2 108 0
MuTect 119 9 115 0
SomaticSniper 116 4 104 0
Strelka 117 0 113 0
Varscan 2 119 6 118 2
  1. FP: false-positive sSNVs; TP: true-positive sSNVs.