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Table 1 The frequencies of estimated 6-SNP haplotypes for the 9p21.3 T2D locus in seven different geographic regions

From: Worldwide patterns of haplotype diversity at 9p21.3, a locus associated with type 2 diabetes and coronary heart disease

rs2383208 rs7045889 rs10811659 rs10757282 rs10811661 rs10757283 Africa N = 102 Middle East N = 160 Europe N = 156 C.S. Asia N = 200 E. Asia N = 229 Oceania N = 28 America N = 63
G A A G C T 0.029 0.197 0.157 0.125 0.393 0.446 0.167
A A A G T* T* 0.118 0.187 0.266 0.221 0.215 0.196 0.206
G G A A T* T* 0.131 0.022 NF NF NF NF NF
A A A A T* T* 0.182 NF NF NF NF NF NF
G A A A T* T* 0.052 NF NF NF NF NF NF
A G A A T C 0.302 0.334 0.308 0.418 0.244 0.089 0.547
A A G A T C 0.022 0.177 0.198 0.199 0.091 0.161 NF
A G G A T C 0.051 0.038 0.046 0.018 0.011 0.071 0.024
G G A A T C 0.042 0.015 NF NF NF NF NF
A A A A T C 0.053 NF NF NF NF NF 0.024
  1. The TT haplotype of SNPs rs10811661 and rs10757283 is the T2D risk haplotype and is in bold-face and marked with an asterisk, while the protective haplotype (GAAGCT) is in bold-face and italicized. Population-specific haplotypes <5% frequent were omitted. NF, haplotype not found in given geographic region.