Skip to main content

Table 2 Additional characteristics of the samples used from the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)

From: A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival

  Breast cancer (#Samples) Methylation signature P value
   Positive (SD) Negative (SD)  
Mean BMI (kg/m2) Yes (119) 27.39 (5.3) 27.27 (5.0) 0.9
  No (121) 26.63 (5.17) 26.57 (4.64) 0.95
Mean age at menarche (years) Yes (117) 12.89 (1.48) 12.65 (1.61) 0.4
  No (122) 12.97 (1.76) 13.24 (1.77) 0.39
Mean age at menopause (years) Yes (119) 49.58 (5.78) 48.37 (7.65) 0.34
  No (122) 47.57 (7.99) 48.74 (5.79) 0.36
  1. The samples were categorised according to their individual risk scores. These risk scores are the product of the methylation profile with the regression coefficients of the signature. The statistical significance was assessed by a t-test. The missing values were excluded from the analysis.