| |
Breast cancer (#Samples)
|
Methylation signature
|
P value
|
|---|
| | |
Positive (SD)
|
Negative (SD)
| |
|---|
|
Mean BMI (kg/m2)
|
Yes (119)
|
27.39 (5.3)
|
27.27 (5.0)
|
0.9
|
| |
No (121)
|
26.63 (5.17)
|
26.57 (4.64)
|
0.95
|
|
Mean age at menarche (years)
|
Yes (117)
|
12.89 (1.48)
|
12.65 (1.61)
|
0.4
|
| |
No (122)
|
12.97 (1.76)
|
13.24 (1.77)
|
0.39
|
|
Mean age at menopause (years)
|
Yes (119)
|
49.58 (5.78)
|
48.37 (7.65)
|
0.34
|
| |
No (122)
|
47.57 (7.99)
|
48.74 (5.79)
|
0.36
|
- The samples were categorised according to their individual risk scores. These risk scores are the product of the methylation profile with the regression coefficients of the signature. The statistical significance was assessed by a t-test. The missing values were excluded from the analysis.
