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Table 4 Genes differentially expressed in common among breast cancer cell lines resistant to MTX

From: Networking of differentially expressed genes in human cancer cells resistant to methotrexate

GenBank Gene name Description Ratio MCF7 Ratio MDA-MB-468
NM_019093 UGT1A1/3/4/5/6/7/8/9/10 UDP glucuronosyltransferase 1, polypeptides A1/3/4/5/6/7/8/9/10 24.36 27.93
NM_000463 UGT1A1/4/6/8/9/10 UDP glucuronosyltransferase 1, polypeptides A1/4/6/8/9/10 15.31 17.66
NM_021027 UGT1A1/4/6/8/9/10 UDP glucuronosyltransferase 1, polypeptides A1/4/6/8/9/10 13.55 17.05
NM_001072 UGT1A1/3/4/5/6/7/8/9/10 UDP glucuronosyltransferase 1, polypeptides A1/3/4/5/6/7/8/9/10 13.21 16.88
AV691323 UGT1A1/3/4/5/6/7/8/9/10 UDP glucuronosyltransferase 1, polypeptides A1/3/4/5/6/7/8/9/10 13.05 16.82
  1. Genes differentially expressed by at least twofold with a P-value < 0.05 including multiple testing correction were compared between MCF7 and MDA-MB-468 cells as described in Table 3.