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Table 5 Genes differentially expressed in common among colon cancer cell lines resistant to MTX

From: Networking of differentially expressed genes in human cancer cells resistant to methotrexate

GenBank Gene name Description Ratio MIA PaCa-2 Ratio K562 Ratio Saos-2
BC003584 DHFR Dihydrofolate reductase 16.97 17.78 4.06
BC000192 DHFR Dihydrofolate reductase 12.56 13.57 5.28
AI144299 DHFR Dihydrofolate reductase 12.1 9.45 8.94
NM_000791 DHFR Dihydrofolate reductase 9.66 6.76 5.57
BE622627 PIK3R3 Phosphoinositide-3-kinase, regulatory subunit 3 5.23 2.09 4.44
AW469790 EEF1A1 Eukaryotic translation elongation factor 1 alpha 1 2.29 2.75 2.05
NM_012446 SSBP2 Single-stranded DNA binding protein 2 2.2 5.04 2.03
AF318326 APG10L ATG10 autophagy related 10 homolog 2.08 7.39 2.19
  1. Genes differentially expressed by at least twofold with a P-value < 0.05 including multiple testing correction were compared between MIA PaCa-2, K562 and Saos-2 cells as described in Table 3.