Figure 5

The survival-network-based landscape of 11 tumour types. Tumour types are self-organised onto a 6 × 6 grid based on mutation frequency and connectivity of genes/nodes in the survival network (see Methods for details). This grid represents the network-based 2D landscape, from which geometric locations delineate relationships between these 11 tumour types. Smaller squares illustrate the same network layout (as in Figure3) but nodes are colour-coded according to tumour-type-specific mutation frequency information. The inset in the top shows the enlarged view for LAML. Abbreviations for these 11 tumour types are: bladder urothelial carcinoma (BLCA); breast adenocarcinoma (BRCA); colon and rectal carcinoma (COADREAD); glioblastoma multiforme (GBM); head and neck squamous cell carcinoma (HNSC); kidney renal clear cell carcinoma (KIRC); acute myeloid leukaemia (LAML); lung adenocarcinoma (LUAD); lung squamous cell carcinoma (LUSC); ovarian serous carcinoma (OV); uterine corpus endometrial carcinoma (UCEC).