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Table 1 Glossary of terms

From: Modules, networks and systems medicine for understanding disease and aiding diagnosis

Term Description
Network A graphical representation of a complex system. For example, in a protein network, proteins are nodes, and interacting proteins are linked by edges
Disease module When mapped onto the protein-protein interaction network, disease-associated genes tend to co-localize and form networks of functionally related genes. These networks are referred to as disease modules
Multilayer disease A module whose nodes and edges are located across different layers of disease-relevant information. Such layers could include transcription factor networks, genetic variants and even environmental factors