SRST2 analysis of hospital outbreak investigation. (a) Isolate genetic profiles obtained from SRST2 analysis, indicating that case EF4 was distinct in both sequence type and resistance gene profile from the outbreak cases EF2 and EF3. Full WGS analysis showed a similar result . (b) Isolate genetic profiles obtained from SRST2 analysis, including plasmid replicons detected (pink). The profiles indicate that case EC3 shared the same sequence type as the linked cases EC1 and EC2 (ST94), but lacked the IncA/C plasmid and had a distinct resistance gene profile. Full WGS analysis showed that EC1 and EC2 isolates were much closer to each other (?22 SNPs) than to EC3 (>150 SNPs) .