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Figure 3 | Genome Medicine

Figure 3

From: Transcriptome-wide signatures of tumor stage in kidney renal clear cell carcinoma: connecting copy number variation, methylation and transcription factor activity

Figure 3

The effects of CNV and methylation on gene expression. (A) Ranked correlations of mRNA expression and CNV (top). The locations of upregulated and downregulated genes and genes in the significantly associated functions are shown in the ranked list (bottom). (B) The distributions of correlations between mRNA expression and CNV for upregulated genes, downregulated genes and all genes. (C) Ranked correlations of mRNA expression and methylation (top). The locations of upregulated and downregulated genes and genes in the significantly associated functions are shown in the ranked list (bottom). (D) The distributions of correlations between mRNA and methylation for upregulated genes, downregulated genes and all genes.

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Genome Medicine

ISSN: 1756-994X

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