Figure 2

Comparison of ClinSeK alignment with BWA. (A) Comparison between ClinSeK and BWA alignment. The numbers are reported from 1,000 sites randomly chosen from the ClinVar database and from 700 samples. Brown color indicates the overlap between ClinSeK and BWA alignments. Green color indicates reads aligned to the target site by only ClinSeK; pink color indicates reads aligned by only BWA. (B) Alignment score distribution of read alignment by only ClinSeK but not BWA aln. The alignment score is calculated by BLAT, with the maximum score of 200 for reads as long as 100 bp.