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Table 4 Top 10 differentially expressed lncRNA and protein-coding genes in inflamed Crohn’s disease

From: Transcriptomic landscape of lncRNAs in inflammatory bowel disease

Gene name Transcript FC
Up-regulated lncRNAs   
  RP11-731 F5.2 ENST00000460164.1 14.14
  MMP12 ENST00000532855.1 6.64
  MMP12 ENST00000326227.5 6.52
  RP11-465 L10.10 ENST00000419897.1 5.69
  RP11-44 K6.2 ENST00000520185.1 3.83
  FAM66D ENST00000526690.1 3.36
  LINC01272 ENST00000445003.1 3.35
  RP11-44 K6.4 ENST00000522970.1 3.24
  SAA2-SAA4 ENST00000524555.1 3.16
  KIF9-AS1 ENST00000429315.2 3.14
Down-regulated lncRNAs   
  DPP10-AS1 ENST00000432658.1 -8.57
  PDZK1P2 ENST00000401008.2 -4.11
  DIO3OS ENST00000553575.1 -3.01
  DIO3OS ENST00000554694.1 -3.01
  DIO3OS ENST00000557532.1 -2.99
  DIO3OS ENST00000557109.1 -2.98
  ANRIL (CDKN2B-AS1) ENST00000422420.1 -2.97
  ANRIL (CDKN2B-AS1) ENST00000428597.1 -2.97
  DIO3OS ENST00000554441.1 -2.96
  DIO3OS ENST00000554735.1 -2.95
Up-regulated protein-coding genes   
  REG3A NM_138938 52.71
  DUOXA2 NM_207581 47.26
  DEFA5 NM_021010 37.73
  DEFA6 NM_001926 28.33
  CHI3L1 NM_001276 26.29
  CXCL1 NM_001511 14.8
  DMBT1 NM_007329 13.45
  SAA1 NM_000331 12.67
  CXCL9 NM_002416 12.07
  IGHG3 ENST00000390551 11.52
Down-regulated protein-coding genes   
  PCK1 NM_002591 -5.55
  SLC26A2 NM_000112 -3.82
  C10orf116 NM_006829 -3.8
  GUCA2B NM_007102 -3.61
  LCN15 NM_203347 -3.43
  AQP7P1 NR_002817 -3.32
  TRPM6 NM_017662 -3.19
  TNNC2 NM_003279 -3.1
  UGT2A3 NM_024743 -2.97
  ADH1C NM_000669 -2.96
  1. Top 10 up- and down-regulated lncRNAs and protein-coding genes in iCD versus control comparison. The log2 fold change is denoted as FC.