JAFFA: High sensitivity transcriptome-focused fusion gene detection

Table 2 A comparison of fusion detection performance on simulated RNA-Seq, 250 bp simulation of 120 fusions

JAFFA and alternative tools were run on a MiSeq simulation of 120 fusions: 20 fusions at each of 1×, 2×, 5×, 10×, 50× and 100× coverage. The simulation included 5 million 250 bp paired-end background reads. In parenthesis we show the value at each of JAFFA’s classifications levels: (high/medium/low) confidence.

ISSN: 1756-994X