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Fig. 3 | Genome Medicine

Fig. 3

From: ENVE: a novel computational framework characterizes copy-number mutational landscapes in colorectal cancers from African American patients

Fig. 3

Modeling of inherent noise in the TCGA CRC WES dataset. a Distribution of exome-wide segmental LogRatios generated using 435 random normal–normal comparisons derived from 30 normal diploid WES samples. b, c Chromosomal coverage by copy-number altered segments at different LogRatio thresholds using the 435 normal–normal comparisons across all chromosomes for the positive (b) and negative (c) LogRatio deviations. Bold horizontal lines within each chromosome indicate the noise-threshold values

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