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Table 3 Genetic annotations for 62 sites selected by recursive Random Forest

From: DNA methylation loci associated with atopy and high serum IgE: a genome-wide application of recursive Random Forest feature selection

CpG Site

Chr

Coordinate

Associated genes

Gene region

CpG island

cg00854799

1

2336398

PEX10; RER1

3′UTR

North Shelf

cg09249800

1

6341287

ACOT7

Body

Island

cg06824199

1

47157809

KIAA0494

Body

cg17594242

1

115654782

cg09332506

1

160309220

COPA

Body

North Shelf

cg01847596

2

95660093

North Shelf

cg07880854

2

112895559

FBLN7

TSS1500

North Shore

cg13168187

2

159523681

PKP4

Body

cg01203365

2

217291500

SMARCAL1

Body

cg27468224

4

55031503

cg11372831

4

57303157

PAICS; PPAT

Body; TSS1500

South Shore

cg03553407

4

148863880

ARHGAP10

Body

cg00528600

5

61699751

DIMT1L

TSS200

Island

cg04085542

5

93414338

FAM172A

Body; 5′UTR

cg05560165

5

133450315

TCF7

TSS1500

Island

cg14322298

6

10585683

GCNT2

Body; TSS1500

cg03131171

6

37616686

MDGA1

Body

North Shore

cg00155310

6

50814011

TFAP2B

3′UTR

South Shore

cg02201050

7

22759083

cg02366798

7

27237154

HOXA13

3′UTR

North Shore

cg09570585

7

138916241

UBN2

1stExon

Island

cg05652668

7

139044807

LUC7L2

1stExon; 5′′UTR

Island

cg07970948

7

149543165

ZNF862

Body

cg24836822

7

150648840

KCNH2

Body

Island

cg05104993

8

11973223

FAM66D

TSS200

North Shore

cg06816054

8

27695695

PBK

TSS1500

South Shore

cg04775941

8

141474793

Island

cg13713293

9

841636

DMRT1

TSS200

Island

cg25854298

10

73936754

ASCC1

Body

cg03468115

10

76852752

cg23527183

10

95253833

North Shelf

cg08397758

10

100174853

PYROXD2

1stExon

cg06851336

10

104678166

CNNM2

1stExon; 5′UTR

Island

cg24077454

10

119134782

PDZD8

1stExon; 5′UTR

Island

cg14574726

11

809735

RPLP2

TSS200

Island

cg12819873

11

57157632

PRG2

5′UTR

cg13233042

11

63432489

ATL3

Body

cg04162999

11

64120313

CCDC88B

Body

cg10016610

11

124735994

ROBO3

Body

Island

cg07908654

13

41631052

North Shelf

cg09635874

13

98952518

FARP1

Body

cg11182893

13

114842103

RASA3

Body

South Shore

cg14478663

14

51643693

cg15281774

15

73661908

HCN4

TSS1500

Island

cg01777765

16

1823191

MRPS34; NME3; EME2

TSS200; TSS1500

Island

cg05048002

16

30077837

ALDOA

5'UTR

Island

cg04342090

16

30670571

Island

cg02775369

16

56316221

GNAO1

Body

cg01190915

16

56642761

MT2A

Body

South Shore

cg04983687

16

88558223

ZFPM1

Body

Island

cg27202913

16

89258862

CDH15

Body

Island

cg01097406

16

89675127

cg04798929

17

8287246

RPL26

TSS1500

Island

cg17549513

17

9694789

DHRS7C

TSS200

cg07765167

17

36451845

MRPL45

TSS1500

North Shore

cg27469152

17

56282313

EPX

3′UTR

cg17041511

17

61509620

North Shelf

cg12819826

19

10216676

PPAN; PPAN–P2RY11

TSS1500; TSS1500

North Shore

cg12578575

19

54135140

DPRX

TSS200

cg11569718

19

58905979

RPS5

Body

North Shore

cg13197551

20

60709957

LSM14B

3′UTR

cg17971837

22

37215996

PVALB

TSS1500

South Shelf

  1. Abbreviations: Chr Chromosome number, CpG cytosine–phosphate–guanineIgE Immunoglobulin E, IOW Isle of Wight cohort, TSS Transcription Start Site, UTR untranslated region
  2. Coordinate: Location of the CpG site within each chromosome, via genome build 37