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Fig. 3 | Genome Medicine

Fig. 3

From: Annotation of pseudogenic gene segments by massively parallel sequencing of rearranged lymphocyte receptor loci

Fig. 3

Percentage of productive rearrangements for individual TCRβ V gene segments. Shown are all TCRβ V gene segments included in this study, classified based on their current IMGT annotation as either functional gene segments (orange), having multiple alleles of differing functionality (teal), or pseudogenes/open reading frames (ORFs; green), sorted by the mean percentage of productive rearrangements within each category. The majority of functional gene segments are found in productive rearrangements most of the time (median 85.5 %). Gene segments with both functional and non-functional alleles display a wide range of productive rearrangements between 15 and 85 %, whereas all gene segments currently annotated as either pseudogenes or ORFs are found in productive rearrangements less than 30 % of the time (median 26.9 %)

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