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Fig. 1 | Genome Medicine

Fig. 1

From: Lower IgG somatic hypermutation rates during acute dengue virus infection is compatible with a germinal center-independent B cell response

Fig. 1

Clinical specimen sampling design and DENV cross-neutralization. a Graphical representation of peripheral blood samples in relation to the onset of symptoms. b Clinical and immune status of patients included in the study. The number of patients in each category during the acute phase is shown. Number of post-convalescent samples is shown in parentheses. c Cross-reactivity of acute DENV infection sera to four serotypes using the DENV reporter virus particle neutralization test. Each bar represents the number of individuals having NT50 > 1:50 to x number of serotypes. DWS− dengue without warning signs; DWS+ dengue with warning signs

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