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Table 2 Gene set enrichment analysis of KR-PAM clusters

From: Identification of key regulators of pancreatic cancer progression through multidimensional systems-level analysis

Name Size ESa NESb Nom P-valuec FDR q-valued
IRS1 47 0.814297 2.749994 0 0
E2F3 83 0.538403 2.012985 0 0
ACTN1 197 0.364171 1.523528 0 0.018332
HMGA2 75 0.401607 1.467728 0.0122378 0.020817
NUAK1 26 0.332612 1.002291 0.4466912 0.4542
DLL1 57 −0.90119 −3.20045 0 0
SKI 133 −0.42133 −1.72121 0 0.001876
RASA1 93 −0.19612 −0.75914 0.9367682 0.91951
  1. a ES Enrichment score showing the maximum deviation from zero based on Kolmogorov-Smirnov statistic
  2. b NES Normalized enrichment score calculated from a null distribution created from 1000 permutations of phenotype labels
  3. c Nominal P-value obtained from the null distribution
  4. d Multiple test corrected P-value
  5. FDR false discovery rate