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Table 1 Sensitivities and specificities for FIT and MMT. The 95 % confidence intervals were computed with 2000 stratified bootstrap replicates

From: Microbiota-based model improves the sensitivity of fecal immunochemical test for detecting colonic lesions

Diagnosis Fecal immunochemical test Multitarget microbiota test
   True positives Sensitivity (95 % CI) True positives Sensitivity (95 % CI)
Cancer n = 120 90 75.0 (67.5–82.5) 110 91.7 (86.7–95.8)
Adenoma n = 198 31 15.7 (10.6–20.7) 90 45.5 (38.4–52.5)
Any lesions n = 318 121 38.1 (32.7–43.4) 200 62.9 (57.2–67.9)
   True negatives Specificity (95 % CI) True negatives Specificity (95 % CI)
Normal n = 172 167 97.1 (94.2–99.4) 155 90.1 (85.5–94.2)