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Table 2 Estimated number of true positives detected in average risk population. Number of true positives identified through FIT and MMT in the United States in adults aged 50–75 years, based on published estimates of CRC prevalence. The sensitivities for FIT (100 ng/mL cutoff) on advanced and non-advanced adenomas were 19.3 % and 11.2 %, respectively

From: Microbiota-based model improves the sensitivity of fecal immunochemical test for detecting colonic lesions

Condition Prevalence Number of persons, aged 50–75 years, with conditiona True positives identified by FIT True positives identified by MMT
Cancer 0.3 % 241,483 181,112 221,359
Advanced adenoma 5.7 % 4,588,174 883,960 2,188,854
Non-advanced adenoma 17.7 % 14,247,488 1,600,841 6,723,534
  1. aNumber of persons in the United States in 2010 aged 50–75 years was 80,494,283