Fig. 5
![Fig. 5](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13073-016-0297-9/MediaObjects/13073_2016_297_Fig5_HTML.gif)
STAT alters microbial communities. a α-diversity of all samples over time, rarefied to a depth of 1014. Only differences observed at week 8 were significant (p <0.05). b STAT exposure and diet corresponding to the PCoA at weeks 4, 11, 16, and 30. c–d PCoAs of beta diversity at weeks 4, 11, 16, and 30. c Control vs. STAT, d healthy vs. disease outcome. p values calculated by Kruskal–Wallis and AUC analysis (*p <0.05; **p <0.01; ***p <0.001). Adonis testing also indicated significant differences (p <0.0005) between the UniFrac distances for the diet:treatment and diet:disease features, when accounting for the repeated measures design (Additional file 3: Table S1)