Table 1 Top regulatory SNVs promoting ER binding in proximity of E2-regulated genes in MCF7 cell line
From: Non-coding single nucleotide variants affecting estrogen receptor binding and activity
Chr location (hg18) | Annotation | Gene | SNV ID | Database | Adjusted p value |
|---|---|---|---|---|---|
chr8:128992864 | ncRNA | PVT1 | NA | TRANSFAC | 2.26E-06 |
chr10:94821513 | Intergenic | CYP26C1;CYP26A1 | rs68040629 | TRANSFAC | 1.10E-05 |
chr15:97136484 | Intronic | IGF1R | rs62022087 | TRANSFAC, JASPAR | 2.03E-05 |
chr10:121292409 | Upstream | RGS10 | rs10787978 | TRANSFAC | 3.39E-05 |
chr6:157157941 | Intronic | ARID1B | rs12208040 | TRANSFAC, JASPAR | 3.63E-05 |
chr11:20014669 | Intronic | NAV2 | rs10741810 | TRANSFAC, JASPAR | 3.65E-05 |
chr17:54818764 | Intronic | YPEL2 | rs8073731 | TRANSFAC, JASPAR | 5.44E-05 |
chr2:10384622 | Intronic | HPCAL1 | rs2014889 | TRANSFAC, JASPAR | 5.62E-05 |
chr4:3456949 | Intronic | DOK7 | rs916189 | TRANSFAC, JASPAR | 1.09E-04 |
chr2:11712184 | Intergenic | GREB1;NTSR2 | rs6432223 | TRANSFAC, JASPAR | 1.13E-04 |