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Table 2 Multivariable regression analyses of potential clinical factors associated with the intra-patient temporal instability of the oral and stool microbiomes of AML patients

From: Characterization of oral and gut microbiome temporal variability in hospitalized cancer patients

  P value
Variables Oral SDI CV Oral UUCV Oral WUCV Stool SDI CV Stool UUCV Stool WUCV
Age 0.287 0.864 0.529 0.425 0.779 0.885
Received piperacillin/tazobactam >72 h 0.475 0.208 0.175 0.507 0.215 0.973
Received cefepime >72 h 0.108 0.557 0.943 0.508 0.669 0.639
Received carbapenem >72 h 0.748 0.762 0.832 0.360 0.482 0.681
Days on all antibioticsa 0.031b 0.0001b 0.002b 0.392 0.858 0.580
Days on treatment antibiotics 0.205 0.060 0.163 0.917 0.633 0.451
Number of antibiotics received 0.089 0.380 0.874 0.357 0.724 0.167
Non-fludarabine high intensity chemotherapy 0.723 0.581 0.935 0.415 0.605 0.456
Hypomethylator-based chemotherapy 0.734 0.712 0.181 0.244 0.900 0.612
  1. a Includes prophylactic antibiotics
  2. b Significant P values
  3. UUCV unweighted UniFrac coefficient of variation, WUCV weighted UniFrac coefficient of variation