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Table 2 List of the five PD-associated CpGs with p value < 10–7 for saliva-based DNA methylation analyses in 259 PEG2 individuals adjusting for age, gender, and race

From: Parkinson’s disease is associated with DNA methylation levels in human blood and saliva

     

Relation to UCSC CpG island

   

Caucasian and Hispanic (N = 259)

 

CpG

Gene

Chr.

Position (bp)

 

Gene region

SNPs

SNPs_10

cor

p value

1

cg15133963

FTHL3

2

27616316

Island

Body

  

−0.35

1.05E-08

2

cg01820192

C21orf125

21

44869762

 

TSS200

  

−0.33

3.45E-08

3

cg22275276

 

6

33973531

    

−0.33

6.92E-08

4

cg11748881

FTH1

11

61734830

Island

1stExon

 

rs11554886

−0.33

7.15E-08

5

cg24742912

MYBPH

1

203146346

 

TSS1500

rs7538338

 

−0.32

9.10E-08

  1. Chr Chromosome, bp base pair, TSS transcription start site, TSS1500 within 1500 bps of a TSS, TSS200 within 200 bps of a TSS, SNPs listing dbSNP entries within a probe, SNPs_10 listing dbSNP entries within 10 bp of the CpG site