Skip to main content

Advertisement

Table 1 Variants in the linkage region after filtering

From: Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer’s disease resilience

SNP Chromosome Position Gene Variant type MAF (controls/cases) MAF (1000 Genomes/ExAC
rs142787485 2 26358156 RAB10 3′ UTR 0.041/0.028 0.0152/NA
rs77747916 2 29405333 CLIP4 3′ UTR 0.0099/0.0069 0.0087/NA
rs41291171 2 33623713 LTBP1 3′ UTR 0.049/0.049 0.0243/NA
rs7653 10 71910316 SAR1A 3′ UTR 0.03/0.0092 0.0175/NA
rs143318821 10 102105884 SCD Promoter NA 0.004/NA
rs41562219 10 103340081 POLL Exonic p.D337D; ncRNA p.D429D 0.0075/0.0080 0.0029/0.0034
chr10:103347900 10 103347900 POLL; DPCD Promoter; 5′UTR 0.0012/0 NA/NA
rs116928523 10 103912209 NOLC1 Exonic p.L14L 0.0075/0.0057 0.003/0.006
  1. For each variant, the dbSNP identifier (SNP), chromosome, position, closest gene(s) (Gene), variant type, minor allele frequency (MAF) in controls and cases, and frequency from the 1000 Genomes Project and Exome Aggregation Consortium (ExAC) are provided (NA if not present in the database)