Fig. 2

The densities of the proportion of risk genes (x-axis) and mean relative risk (y-axis) for SCZ data. These were obtained after 20,000 iterations of three MCMC chains. The first two case–control populations are derived from the Sweden data set while the third case–control population is the UK population. The scales on the y-axes are adjusted because mean relative risk varies between categories. LoF loss of function, MCMC Markov chain Monte Carlo, MiD missense damaging, Pop population, SCZ schizophrenia, silentFCPk, silent within frontal cortex-derived DNase I hypersensitive site peaks