Table 3 Top significant associations of psychiatric and behavioral polygenic risk scores (PRSs) with the 13 local-adaptation variables identified. Abbreviations are reported in Table 1 and Table 2
Local-adaptation variable | PRS | PT | SNP N | R 2 | Z score | p value | q value |
|---|---|---|---|---|---|---|---|
MaxSunnyDaylight | BD | 0.01 | 2833 | 0.09% | −2.93 | 3.42 × 10−3 | 0.043 |
Consonants | CONS | 0.5 | 60,620 | 0.28% | −2.97 | 2.98 × 10−3 | 0.043 |
Latitude | DS | 10−7 | 1 | 0.09% | 3.47 | 5.38 × 10−4 | 0.029 |
SumMaxTemp | 0.12% | −3.40 | 6.91 × 10−4 | 0.029 | |||
MinPrecipRate | 0.05 | 12,832 | 0.27% | −3.29 | 1.03 × 10−3 | 0.029 | |
MaxPrecipRate | MDD | 0.3 | 39,390 | 0.31% | −3.21 | 1.33 × 10−3 | 0.034 |
Altitude | 1 | 97,481 | 0.31% | −3.13 | 1.79 × 10−3 | 0.037 | |
ProtozoaDiversity | OPEN | 10−6 | 2 | 0.18% | 3.56 | 3.82 × 10−4 | 0.029 |
SumMinTemp | 5 × 10−8 | 1 | 0.18% | 2.7 | 3.02 × 10−3 | 0.043 | |
WinMinTemp | SCZ | 0.5 | 104,106 | 0.40% | 3.84 | 1.28 × 10−4 | 0.029 |
Longitude | 0.13% | −3.29 | 1.01 × 10−3 | 0.029 | |||
WinMaxTemp | 0.12% | 2.96 | 3.09 × 10−3 | 0.043 | |||
MinRelHumidity | SWB | 10−6 | 4 | 0.21% | −2.95 | 3.22 × 10−3 | 0.043 |