Fig. 5
From: KLRD1-expressing natural killer cells predict influenza susceptibility
KLRD1 expression increases in tissue during viral infection and inversely correlates with symptom severity. KLRD1 expression over the course of viral challenge in a discovery challenges A, B, and C and b validation cohort GSE61754. c Forest plot of KLRD1 expression in human nasal epithelium infected with human rhinovirus (HRV), respiratory syncytial virus (RSV), or a co-infection of RSV with other pathogens (RSVco) (GSE11348, GSE97742; effect size = 0.77, P = 0.001). d Correlation between logged total symptom score and KLRD1 expression in the nasal epithelium 8 h after HRV challenge (GSE11348; r = − 0.6, P = 0.031). e–f Correlation between KLRD1 expression and KLRC3 (r = 0.82, P = 0.00065) or HLA-E (r = 0.76, P = 0.0028) expression in the nasal epithelium 8 h after HRV challenge (GSE11348)