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Fig. 5 | Genome Medicine

Fig. 5

From: KLRD1-expressing natural killer cells predict influenza susceptibility

Fig. 5

KLRD1 expression increases in tissue during viral infection and inversely correlates with symptom severity. KLRD1 expression over the course of viral challenge in a discovery challenges A, B, and C and b validation cohort GSE61754. c Forest plot of KLRD1 expression in human nasal epithelium infected with human rhinovirus (HRV), respiratory syncytial virus (RSV), or a co-infection of RSV with other pathogens (RSVco) (GSE11348, GSE97742; effect size = 0.77, P = 0.001). d Correlation between logged total symptom score and KLRD1 expression in the nasal epithelium 8 h after HRV challenge (GSE11348; r = − 0.6, P = 0.031). ef Correlation between KLRD1 expression and KLRC3 (r = 0.82, P = 0.00065) or HLA-E (r = 0.76, P = 0.0028) expression in the nasal epithelium 8 h after HRV challenge (GSE11348)

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