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Fig. 3 | Genome Medicine

Fig. 3

From: Integrative omics analyses broaden treatment targets in human cancer

Fig. 3

Repurposing of drugs using common mutations associated with drug sensitivity. Cancer-type-specific mutations (blue) and cancer-type-non-specific mutations (red) are distinguished. Intensity of shading corresponds to the fraction of tumors for a given cancer type (x-axis) that contain a specific drug-associated mutation (y-axis). Drug classes associated with each cancer-type-specific mutation from DEPO are shown in the right panel. Only drug-associated mutations present in the largest number of tumor samples across the TCGA cohort are displayed

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