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Table 3 Maternal-specific allele-based proportion of genetic variance and fetal-specific allele-based proportion of genetic variance for maternal and neonatal chemokines and cytokines under a no dosage compensation model

From: Cross-genetic determination of maternal and neonatal immune mediators during pregnancy

SIM Dataset Maternal-only non transmitted allele Fetal-only non inherited allele
V (g) /Vp SE P value V (g) /Vp SE P value
Chemokines
 CXCL10 Mothers 0.81 0.19 7.1 × 10−3 0.81 0.20 0.01
 CCL1 Infants 0.63 0.31 0.09 0.75 0.26 0.04
 CCL3 Infants 0.47 0.40 NS 0.41 0.44 NS
 CCL17 Infants 0.75 0.25 0.05 0.81 0.22 0.02
 CCL19 Infants 0.80 0.23 0.03 0.83 0.21 0.01
 CCL22 Infants 0.95 0.16 2.8 × 10−3 0.83 0.22 0.02
 CCL25 Infants 0.48 0.37 NS 0.39 0.44 NS
 CXCL5 Infants 0.87 0.20 0.025 0.45 0.41 NS
Cytokines
 IL-4 Infants 0.49 0.40 NS 0.00 0.73 NS
 IL-7 Mothers 0.79 0.21 0.0163 0.99# 0.17 < 0.01
  1. V(g)/Vp proportion of genetic variance over phenotypic variance
  2. #Fisher’s test applied for non converging models
  3. NS not significant