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Table 1 Clinical characteristics of patients diagnosed with stage III, grade III, serous ovarian epithelial cancer at Princess Margaret by length of survival

From: Landscape of genomic alterations in high-grade serous ovarian cancer from exceptional long- and short-term survivors

Covariate Full Sample (n = 41) LT (n = 20) ST (n = 21) p value
Number of patients 41 20 21  
Stage III, HGSOC 41 (100) 20 (49) 21 (51)  
Overall Survival < 0.001
 < 6 months 0 (0) 0 (0) 0 (0)  
 6–12 months 2 (5) 0 (0) 4 (19)  
 12–24 months 19 (46) 0 (0) 17 (81)  
 > 24 months 20 (49) 20 (100) 0 (0)  
Age at diagnosis 0.024
 Mean (sd) 59 (9.3) 56.1 (9.4) 61.7 (8.7) 0.024
 Median (min,max) 57 (40,84) 55.5 (40,84) 59 (47,76)  
Residual disease 0.012
 No 18 (44) 13 (65) 5 (24)  
 Yes 23 (56) 7 (35) 16 (76)  
Disease recurrence < 0.001
 No 17 (41) 17 (85) 0 (0)  
 Yes 24 (59) 3 (15) 21 (100)  
Number of disease recurrence < 0.001
 0 17 (41) 17 (85) 0 (0)  
 1 15 (37) 1 (5) 14 (67)  
 2 7 (17) 1 (5) 6 (29)  
 > 2 2 (5) 1 (5) 1 (5)  
CA125 at diagnosis 0.39
 Mean (sd) 1207 (1781.6) 870.4 (863.1) 1491 (2277.9)  
 Median (min,max) 475 (67,9162) 585 (67,2700) 399 (184,9162)  
 Missing 6 4 2  
CA125 at diagnosis rate 0.41
 Unknown 6 (15) 4 (20) 2 (10)  
 0–35 U/mL 0 (0) 0 (0) 0 (0)  
 > 35 U/mL 35 (85) 16 (80) 19 (90)  
CA125 post-surgery < 0.001
 Mean (sd) 421 (932.4) 63.9 (74.8) 799.1 (1243.4)  
 Median (min,max) 121 (7,4712) 33 (7299) 296 (53,4712)  
 Missing 6 2 4  
CA125 post-surgery rate < 0.001
 Unknown 6 (15) 2 (10) 4 (19)  
 0–35 U/mL 9 (22) 9 (45) 0 (0)  
 > 35 U/mL 26 (63) 9 (45) 17 (81)  
CA125 post chemotherapy < 0.001
 Mean (sd) 656.4 (3772.9) 4.6 (2.1) 1308 (5325.7)  
 Median (min,max) 6.5 (2,23,290) 4 (2,10) 18 (4, 23,287)  
 Missing 3 1 2  
CA125 post chemotherapy rate 0.0063
 Unknown 3 (7) 1 (5) 2 (10)  
 0–35 U/mL 31 (76) 19 (95) 12 (57)  
 > 35 U/mL 7 (17) 0 (0) 7 (33)  
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