Skip to main content

Table 2 Cross-validation performance of models trained on binding affinity (BA) or eluted ligand (EL) data

From: Footprints of antigen processing boost MHC class II natural ligand predictions

BA single models EL single models
Training set AUC AUC 0.1 Training set AUC AUC 0.1 PPV
DR1 BA 0.84 0.374 DR1 Ph 0.96 0.819 0.773
DR1 Pm 0.986 0.888 0.815
DR1 Sm 0.977 0.851 0.794
DR15 BA 0.843 0.287 DR15 Ph 0.987 0.901 0.85
DR15 Pm 0.989 0.917 0.859
DR51 BA 0.846 0.38 DR51 Ph 0.961 0.759 0.717
  1. For BA (“BA single models”), the training performance is reported in terms of AUC and AUC 0.1. For EL (“EL single models”), values for AUC, AUC 0.1, and PPV are displayed. For references on the training sets names and compositions, refer to Table 1. For information regarding the performance metrics, see the “Performance metrics” section in the “Methods” section