Skip to main content

Advertisement

Table 4 Molecular characterization of patient-derived xenografts

From: Evolving neoantigen profiles in colorectal cancers with DNA repair defects

Sample MSI status BRAF KRAS NRAS MLH1 MSH2 MSH3 MSH6 PMS2 POLE
CRC106 MSI V600E WT WT WT WT WT R577H / p.T1085Tfs7* WT WT
CRC542 MSS WT WT WT WT WT WT WT WT WT
CRC371 MSS WT WT E132K R265C WT WT E946* WT V411 L
  1. *Only non-synonymous variants present in COSMIC database are reported