Fig. 4
From: Comparative analysis of functional assay evidence use by ClinGen Variant Curation Expert Panels
Representative findings from the curation of specific instances of MYH7 functional assays. We assessed the following methods and validation parameters of variant-specific knock-in mouse models, ATPase activity, and motility assays: experimental material, controls, replication, and output. *Assays not approved by the Variant Curation Expert Panel (VCEP). †Specific instance of assay cited by the VCEP as evidence for the PS3/BS3 criteria in pilot variant classification, see Additional file 2: Tables S6 and S7 for the primary literature curation results