Table 1 Demographics of exome-sequenced adult BioMe Biobank participants and of individuals harboring expected pathogenic variants in BRCA1/2
|  | Sequenced BioMe participants (N = 30,223) | BRCA1/2 variant negative (N = 27,060)* | BRCA1/2 variant positive (N = 218) |
|---|---|---|---|
Age, median (IQR) | 59 (45–70) | 59 (46–70) | 58 (43–70) |
Female, N (%) | 17,914 (59.3) | 15,986 (59.1) | 137 (62.8) |
Self-reported ancestry, N (%) | |||
 African American/African | 6878 (22.8) | 5877 (28.3) | 33 (15.1) |
 East/Southeast Asian | 757 (2.5) | 659 (3.2) | 6 (2.8) |
 European | 7772 (25.7) | 7265 (35.0) | 121 (55.8) |
 Hispanic/Latino | 10,460 (34.6) | 9360 (45.1) | 34 (15.6) |
 Native American | 52 (0.2) | 47 (0.2) | 0 (0) |
 South Asian | 605 (2.0) | 543 (2.6) | 0 (0) |
 Other | 2343 (7.8) | 2111 (10.2) | 13 (6.0) |
 Multiple selected | 1125 (3.7) | 1006 (4.9) | 10 (4.6) |
 Not available | 231 (0.8) | 192 (0.9) | 1 (0.5) |